Raphael is an Archangel mentioned in Darksiders III.
According to Jamaerah, Raphael created the healing shards that allow anyone who possess them to be fully cured of any affliction. He did that by weaving a strand of the life-force that powered Creation itself into them.
Raphael is a kind-hearted angel, as it is said that healing is his nature.
As an Archangel and a being able to weave the life-force of Creation, Raphael is undoubtedly an extremely powerful entity.