"All of creation cares not whether you live or die."
Hell, also known as The Second Kingdom and The Dark Kingdom, is the Second Realm that makes up the Universal Balance in the Darksiders Verse. Hell is, as its name suggests, the home of the Demonic hordes and from where many Demons spawn into existence. The forces of Hell on Earth are controlled by the powerful entity known as the Destroyer, who tasked his champion Straga to claim the Third Kingdom, Earth, for the might of the demonic legions in their incessant struggle against the denizens of the First Kingdom of Heaven, the Angel Race, their immortal enemy that has been warring with the demonic forces for millennia.
Not much is known about the layout of Hell other than that is it a vast chaotic realm filled with countless domains and demons fighting each other for dominance. It is implied it may consist of Nine layers or domains when The Watcher mentions it as such when Samael opened the portal to the Black Throne for War. Demons, such as Vulgrim, do occupy realms outside of Hell and claim dominion of them as their own. Death visited the demon Samael's domain in Shadow's Edge, though little of it was explored beyond Samael's fortress of Black Stone.
Hell is ruled by an entity known as the 'Dark Prince', who was referenced by Vulgrim as a being that Samael may have been a threat to. Though many demons fight for control of Hell and as such the dominion of Hell is always available to the strongest of Demons.